How atherosclerosis develops

I continue to read Deep Nutrition by Catherine Shanahan MD. According to Dr. Shanahan, the most dangerous foods are vegetable oils, sugars, and foods that convert to sugar during digestion. She gave an interesting description of how the two combine to create coronary artery disease. I’ve never seen it laid out quite the same before. It’s a very compelling description of the process if it’s true. It actually explains how the epithelial lining of the arteries becomes injured in the first place, which is something other explanations fail to do.

To sum it up, sugar in the bloodstream damages lipoproteins (HDL, LDL, VLDL). The lipoproteins, in turn, spill their loads into the bloodstream where it should not be. If that load contains mega-trans-fats from damaged vegetable oils (which happens when heat is applied, either during production or cooking), those fats cause oxidative damage to the fats in the membranes of the cells of the epithelial lining of the arteries, resulting in a literal burning of the cells. Gruesome! The body then attempts to repair that damage by sending cholesterol and white blood cells to the injured site. These repairs become the arterial plaques of atherosclerosis.

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